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T7625 |
TRAP-6
|
PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA) |
Protease-activated Receptor
|
|
TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1). |
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T7137 |
I-191
|
|
Protease-activated Receptor
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I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells. |
|
TQ0012 |
AZ3451
|
|
Protease-activated Receptor
|
|
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM). |
|
T1986L |
Atopaxar Hydrobromide
|
|
Protease-activated Receptor
|
|
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. |
|
T1986 |
Atopaxar
|
E5555,ER-172594-00 |
Protease-activated Receptor
|
|
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. |
|
T2370 |
AC-55541
|
AOB2796 |
Proteasome
,
Protease-activated Receptor
|
|
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. |
|
T12870 |
SCH79797 dihydrochloride
|
|
Apoptosis
,
Others
,
Protease-activated Receptor
|
|
SCH79797 dihydrochloride is a selective antagonist of nonpeptide protease activated receptor 1 (PAR1). |
|
TP1046 |
SLIGRL-NH2
|
Protease-Activated Receptor-2 Activating Peptide |
Protease-activated Receptor
|
|
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus. |
|
T7013 |
Vorapaxar
|
SCH 530348,MK-5348 |
Protease-activated Receptor
|
|
Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM). |
|
T1893 |
Parmodulin 2
|
ML 161 |
Protease-activated Receptor
|
|
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb... |
|
T8917 |
PAR-2-IN-1
|
IUN76750 |
Protease-activated Receptor
|
|
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects. |
|
T3098 |
Vorapaxar sulfate
|
SCH 530348 sulfate,Zontivity,vorapaxar monosulfate |
Protease-activated Receptor
|
|
Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist. |
|
TP1065 |
PAR-4 Agonist Peptide, amide TFA
|
PAR-4-AP (TFA),AY-NH2 (TFA) |
Protease-activated Receptor
|
|
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited b... |
|
T7496 |
Thrombin Receptor Activator for Peptide 5 (TRAP-5)
|
Thrombin Receptor Activator for Peptide |
Protease-activated Receptor
|
|
Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in coronary heart disease (CHD) research. |
|
T7513 |
Protease-Activated Receptor-2, amide
|
SLIGKV-NH2 |
Protease-activated Receptor
|
|
Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M) |
|
T7623 |
PAR-4 Agonist Peptide, amide
|
AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP |
Protease-activated Receptor
|
|
PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4). |
|
T4186 |
AC-264613
|
AC264613 |
Protease-activated Receptor
|
|
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha... |
|
T7380 |
Protease-Activated Receptor-4
|
|
Protease-activated Receptor
|
|
Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy |
|
T7573 |
TFLLR-NH2
|
TFLLR-NH2(2TFA) |
Protease-activated Receptor
|
|
TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM). |
|
T80240 |
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
|
|
|
|
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype of G-protein coupled receptors involved in mediating thrombin... |
|
T36101 |
Psychotridine
|
|
|
|
Psychotridine is an alkaloid that has been found inP. forsterianaand has diverse biological activities.1,2,3It inhibits ADP-, collagen-, or thrombin-induced aggregation of washed isolated human platelets with IC50values ... |
|
T36717 |
RWJ-56110 dihydrochloride
|
|
|
|
RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits... |
